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Life Goals Collaborative Care (Life Goals) is an evidence-based program shown to improve health outcomes for persons with mood disorders in six separate randomized controlled trials. A central tenet of the program is reducing the separation between physical and mental health through integrated psychotherapy and collaborative care management. Life Goals improved outcomes, especially for persons with co-occurring medical or substance use disorders:

                        • For every 10 receiving Life Goals, 1 reduced their 10-year risk of cardiovascular disease
                        • Life Goals helped reduced high blood pressure, which can reduce the risk of mortality
                        • Life Goals reduced depressive symptoms and improved overall functioning

Life Goals includes brief modules ranging from depression symptom coping strategies to managing comorbid conditions. The core modules help persons with mood disorders achieve personal goals by linking them to tailored health behavior change and symptom coping strategies.

A workbook based on Life Goals is also available (“Overcoming Bipolar Disorder: A Comprehensive Workbook on Managing Your Symptoms and Achieving Your Life Goals”).

Overcoming Bipolar Disorder workbook


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Life Goals was recently added to SAMHSA’s National Registry of Evidenced-Based Programs and Practices (NREPP)

Life Goals – NREPP

Below is a selection of Life Goals publications:

                        • Kilbourne AM, Post EP, Nossek A, et al. Improving medical and psychiatric outcomes among individuals with bipolar disorder: a randomized controlled trial. Psychiatr Serv 2008;59:760-8. pdf
                        • Bauer MS, McBride L, Williford WO, et al. Collaborative care for bipolar disorder: part I. Intervention and implementation in a randomized effectiveness trial. Psychiatr Serv. 2006;57:927-36. pdf
                        • Bauer MS, McBride L, et al. Collaborative care for bipolar disorder: Part II. Impact on clinical outcome, function, and costs. Psychiatr Serv. 2006;57:937-45. pdf
                        • Simon GE, Ludman EJ, Bauer MS, et al. Long-term effectiveness and cost of a systematic care program for bipolar disorder.  Arch Gen Psychiatry. 2006;63:500-8. pdf
                        • Kilbourne AM, Biswas K, Pirraglia PA, et al. Is the collaborative chronic care model effective for patients with bipolar disorder and co-occurring conditions? J Affect Disord. 2009;112: 256-61. pdf
                        • Kilbourne AM, Goodrich D, Lai Z, et al. Randomized Controlled Pilot Study of Life Goals Collaborative Care for Patients with  Bipolar Disorder and Cardiovascular Disease Risk from Community Practices. Psychiatric Services , 2012 pdf
                                  • Kilbourne AM, Li D, Lai Z, et al  Pilot Randomized Trial of a Cross-Diagnosis Collaborative Care Program for Patients with Mood Disorders. Depression and Anxiety, 2013 pdf
                                  • Kilbourne AM, Goodrich DE, Lai Z, et al. Randomized controlled trial to assess reduction of cardiovascular disease risk in patients with bipolar disorder: the Self-Management Addressing Heart Risk Trial (SMAHRT). J Clin Psychiatry 2013; 74: 655-662. pdf

Life Goals bibliography pdf

The Life Goals Privacy Policy pdf